These new dyes offered by MTTI belong to the family of encapsulated dyes
known as the Squaraine Rotaxanes.
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Advantages Include:

  • Improved chemical and photochemical stability compared with squaraines, cyanines, AlexaŽ and Atto dyes.
  • Exhibit sharp absorption and emission bands thus provide reduced excitation and emission cross talk into channels where other fluorochromes are being used.
  • Do not exhibit aggregation induced spectral broadening under biological conditions at micromolar concentrations.
  • 5-20X brighter compared with cyanines, AlexaŽ and Atto dyes.
  • Photophysical properties stable over the pH range from 2-12.
  • Spectral properties compatible with the 633nm or 647nm laser lines on flow cytometers, confocal and in vivo imaging equipment.

Recent Publications

Custom Squaraine Rotaxane Dyes Also Prepared!

     
 
Catalog
Number
Name Description Size Price (USD)
SR-1001

SRfluor® 680
Phenyl

Crystalline Powder

product insert pdf

Lipophilic squaraine rotaxane analog that emits in the far-red region of the spectrum and is known to accumulate at lipophilic sites inside living cells. Spectral properties: abs max = 650 nm and emission max = 678 nm in DMSO. 1mg $162.50
SR-1002

SRfluor® 680
Carboxyl

Crystalline Powder

product insert pdf

Carboxyl functionalized squaraine rotaxane analog that emits in the far-red region of the spectrum. Spectral properties: abs max = 650 nm and emission max = 678 nm in DMSO. This compound can be readily coupled to amino functionalities of biomolecules to provide fluorescent conjugates for use in multiple applications. 1mg $187.50
SR-1003

SRfluor® 680

Crown

Crystalline Powder

product insert pdf

Squaraine rotaxane analog that emits in the far-red region of the spectrum and is functionalized with a crown ether which can bind to cations such as Na+ and K+. Spectral properties: abs max = 641 nm and emission max = 661 nm in ethanol. 1mg $213.00
SR-1004

SRfluor® 680
maleimide

Crystalline Powder

product insert pdf

Squaraine rotaxane analog that emits in the far-red region of the spectrum and is functionalized with a maleimide group that can readily undergo conjugation with thiol groups. Spectral properties:abs max = 641 nm and emission max = 664 nm in ethanol. 1mg $241.00
SR-1005

SRfluor® 680
NHS ester

Crystalline Powder

product insert pdf

Squaraine rotaxane analog that emits in the far-red region of the spectrum and is functionalized with a hydroxysuccinimide ester group that can readily undergo conjugation with amino groups of biomolecules to provide fluorescent conjugates for use in multiple applications. Spectral properties: abs max = 650 nm and
emission max = 678 nm in DMSO.
1mg $213.00
SR-1006

SRfluor® 680
azide

Crystalline Powder

product insert pdf

Squaraine rotaxane analog that emits in the far-red region of the spectrum and is functionalized with an azide group that can readily undergo click chemistry reactions with reagents or biomolecules with a terminal alkyne group to provide fluorescent conjugates for use in multiple applications. A free carboxyl group is also present in this molecule which can be coupled to amino groups of biomolecules. Spectral properties: abs max = 645 nm and emission max = 668 nm in DMSO. 1mg $213.00
SR-1007

SRfluor® 680
alkyne

Crystalline Powder

product insert pdf

Squaraine rotaxane analog that emits in the far-red region of the spectrum and is functionalized with a terminal alkyne group that can readily undergo click chemistry reactions with reagents or biomolecules with an azide group to provide fluorescent conjugates for use in multiple applications. Spectral properties: abs max = 649 nm and emission max = 673 nm in DMSO. 1mg $213.00

AlexaŽ is a trademark of Molecular Probes, a subsidiary of Invitrogen.

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