Cyanine dyes exhibit large molar absorptivities (~150,000-250,000M-1cm-1) and moderate quantum yields resulting in extremely bright fluorescence signals. Therefore, cyanines have proven useful in several fields including photography, biology, laser technology and analytical chemistry.

MTTI offers a series of unique lipophilic cyanine dyes which maybe useful for biophysical studies of lipid bilayers of cells or other artifical membranes. In particular, these compounds maybe useful as molecular probes of membrane potential, for labeling lipid bilayers and for labeling hydrophobic pockets of lipo-proteins.

MTTI also offers several substituted indole derivatives which can be used as building blocks for the construction of new cyanine dye derivatives for use in the aforementioned fields.

Custom Cyanine Dyes Also Prepared!

Some Recent Cyanine Dye Publications:

• Bouteiller C et al. Novel Water Soluble Near-Infrared Cyanine Dyes: Synthesis, Spectral Properties, and Use in the Preparation of Internally Quenched Fluorescent Probes. Bioconjugate Chemistry, 18 (4), 1303-1317 (2007).
• Pham W et al. Synthesis and Applications of a Water Soluble Near Infrared Dye for Cancer Detection Using Optical Imaging. Bioconjugate Chemistry, 16 (3), 735-740 (2005).
• Hilderbrand SA et al. Monofunctional Near-Infrared Fluorochromes for Imaging Applications. Bioconjugate Chemistry, 16 (5), 1275-1281 (2005).
• Ye Ye et al. Multivalent Carbocyanine Molecular Probes: Synthesis and Applications. Bioconjugate Chemistry, 16(1), 51-61, (2005)

* Purity of all compounds >95%